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Study: Aggressive Cancer Can be Treated by Targeting Rogue DNA
Image credit: Pascal Pochard-Casabianca/Contributor/AFP via Getty Images

Study: Aggressive Cancer Can be Treated by Targeting Rogue DNA

Researchers from the UK and US have found that treating the most aggressive cancers should focus on targeting extrachromosomal DNA (ecDNA), which are "rogue" DNA fragments that help cancerous tumors flourish and become chemotherapy-resistant.

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by Improve the News Foundation

Facts

  • Researchers from the UK and US have found that treating the most aggressive cancers should focus on targeting extrachromosomal DNA (ecDNA), which are "rogue" DNA fragments that help cancerous tumors flourish and become chemotherapy-resistant.[1]
  • They found ecDNA is present in over 17% of analyzed tumors, particularly in aggressive forms of breast, brain, and lung cancers.[1][2]
  • This rogue DNA, which is found across 39 cancer types, also amplifies immunomodulatory and inflammatory genes, which contribute to treatment resistance, immune evasion, and cancer spreading to other parts of the body.[3]
  • However, the researchers developed a "CHK1 inhibitor" — which helps repair damaged cells — to specifically target ecDNA-containing cancer cells, reducing tumor growth and preventing resistance.[4][5]
  • This comes amid similar research out of Munich, Germany, where researchers are developing microrobots to deliver treatments directly to tumor cells. Those scientists created soft microrobots — which they describe as similar to cells — that can be controlled wirelessly.[6]

Sources: [1]The Guardian, [2]Nature (a), [3]Nature (b), [4]NCBI, [5]Nature (c) and [6]DW.

Narratives

  • Establishment-critical narrative, as provided by X and Pharma Manufacturing. While cancer treatments are currently necessary for a lot of people, the most important thing to focus on is how to prevent the next generation of cancer patients. This horrific disease should not be as widespread as it is, and the medical establishment is choosing to prescribe profitable medications rather than focus on the root causes. Our food supply and environment are chock-full of toxins that are destroying human cells. If we got rid of those toxins, we could put a major dent in the cancer epidemic.
  • Pro-establishment narrative, as provided by WebMD. DNA treatments are the future of cancer therapy, as they precisely target the root epigenetic changes that drive tumor growth without damaging healthy cells. Unlike traditional treatments like chemotherapy, which indiscriminately kills cells, epigenetic drugs can restore normal gene function by reversing harmful DNA modifications. This will make cancer treatment more efficient while also reducing negative symptoms.
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by Improve the News Foundation

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