Malaria Vaccine Debuts in Africa

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Facts

  • 'A monumental milestone' in the battle against malaria was set Monday with the rollout of the 'R21/Matrix-M' vaccine in the West African nation of the Ivory Coast.1
  • Co-developed by the University of Oxford and the Serum Institute of India, the vaccine is targeted to immunize around 6.6M children in 15 African nations from 2024-25.2
  • The jab which costs less than $4 per dose, is the second such vaccine. 'RTS,S,' launched earlier this year, costs twice as much and reportedly faces manufacturing hurdles.3
  • The World Health Organization has recommended this vaccine for children aged under five in Africa, where the disease kills over 600K people in that age group each year.4
  • At the peak of the COVID pandemic, malaria reportedly killed more people there than the coronavirus across Africa.5
  • Pointing to Africa's decades-long struggle with malaria, Sania Nishtar — chief executive of Gavi, the Vaccine Alliance — said R21/Matrix-M could potentially 'turn the tide.'1

Sources: 1NDTV.com, 2University of Oxford, 3Daily Mail, 4Bloomberg and 5The Times.

Narratives

  • Narrative A, as provided by Lowestoft Journal. R21/Matrix-M promises to significantly advance efforts to eradicate malaria. Meeting the WHO’s 75% efficacy target, the vaccine is a ground-breaking achievement. At under $4 per dose, it's extremely affordable. The vaccine targets malaria pathogens early and induces a strong immune response — potentially cutting annual deaths from 500K to 200K this decade and eliminating the disease by the next.
  • Narrative B, as provided by Guardian. R21/Matrix-M is not a cure-all. It offers up to 75% protection in trials, but real-world effectiveness may be lower, especially in impoverished regions. While it may be vital, this vaccine alone won't end malaria. Challenges include the need for multiple doses, potential difficulties in maintaining vaccination schedules, and reliance on other measures like bed nets and effective treatments. Battling malaria requires a consistent, multi-front offensive.

Predictions